Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:1321268 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
132126813226381371adenylosuccinate lyaseQuickGO ontologyBLASTP
13226421323283642hypothetical proteinBLASTP
132337013244761107tRNA 5-methylaminomethyl-2-thiouridylate-methyltransferaseQuickGO ontologyBLASTP
13245301324991462hydrolase NUDIX familyQuickGO ontologyBLASTP
13250031325332330putative secreted proteinQuickGO ontologyBLASTP
13253291326066738ribosomal large subunit pseudouridine synthase EQuickGO ontologyBLASTP
132616613274161251isocitrate dehydrogenase NADP-dependentQuickGO ontologyBLASTP
132786413289881125putative cytoplasmic proteinQuickGO ontologyBLASTP
13290201329178159hypothetical proteinBLASTP
13299791330767789EnvFQuickGO ontologyBLASTP
13316861332207522EnvEQuickGO ontologyBLASTP
13328761333004129hypothetical proteinBLASTP
13335341333662129hypothetical proteinBLASTP
13340421334599558virulence membrane protein PagCQuickGO ontologyBLASTP
13358211336165345putative periplasmic proteinQuickGO ontologyBLASTP
13365431336668126hypothetical proteinBLASTP
13368001336973174hypothetical proteinBLASTP
13372901337760471heat shock proteinQuickGO ontologyBLASTP
133809913391421044putative cytoplasmic proteinQuickGO ontologyBLASTP