Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:1209935 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
120993512138973963bifunctional protein PutAQuickGO ontologyBLASTP
121431912158271509sodiumproline symporterQuickGO ontologyBLASTP
12176141218495882transcriptional regulator RpiR familyQuickGO ontologyBLASTP
121878112202771497sodium-glucosegalactose cotransporterQuickGO ontologyBLASTP
12206141221294681bifunctional enzyme NanEnanKQuickGO ontologyBLASTP
122180012229601161kelch domain-containing protein YjhTQuickGO ontologyBLASTP
12230061223698693oligogalacturonate-specific porinQuickGO ontologyBLASTP
122398112252611281putative metabolite transport protein YjhBQuickGO ontologyBLASTP
122527512263781104putative oxidoreductase YjhCQuickGO ontologyBLASTP
12266891226853165hypothetical proteinBLASTP
12268521227790939putative 2-hydroxyacid dehydrogenase YcdWQuickGO ontologyBLASTP
12278751228612738putative hydrolaseQuickGO ontologyBLASTP
12286361229190555chaperone TorD familyQuickGO ontologyBLASTP
12292791229773495inner membrane protein YcdZQuickGO ontologyBLASTP
12298121230645834curli production assemblytransport component CsgGQuickGO ontologyBLASTP
12306721231088417curli production assemblytransport component CsgFQuickGO ontologyBLASTP
12311151231510396curli production assemblytransport component CsgEQuickGO ontologyBLASTP
12315151232165651transcriptional regulator CsgDQuickGO ontologyBLASTP
12329201233375456minor curlin protein CsgBQuickGO ontologyBLASTP
12334171233872456major curlin subunitQuickGO ontologyBLASTP
12339341234260327curli production protein CsgCQuickGO ontologyBLASTP
12343911234711321hypothetical proteinBLASTP