Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:1166951 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
116695111680181068putative bacteriophage proteinQuickGO ontologyBLASTP
11681831168347165putative secreted proteinQuickGO ontologyBLASTP
11684311168886456hypothetical protein
11690051169757753putative bacteriophage proteinQuickGO ontologyBLASTP
11697571170110354putative bacteriophage proteinQuickGO ontologyBLASTP
117011111713101200putative bacteriophage proteinQuickGO ontologyBLASTP
11713071171987681putative bacteriophage proteinQuickGO ontologyBLASTP
117198711735191533side tail fiber proteinQuickGO ontologyBLASTP
11735251174052528caudovirales tail fibre assembly proteinQuickGO ontologyBLASTP
11743411174466126hypothetical protein
11745191175157639phage tail assembly proteinQuickGO ontologyBLASTP
11752671175659393hypothetical proteinBLASTP
11765251176944420hypothetical proteinBLASTP
11778841178387504pathogenicity island-encoded protein AQuickGO ontologyBLASTP
11787861179661876secreted effector proteinQuickGO ontologyBLASTP
11802091180550342chaperone protein SigEQuickGO ontologyBLASTP
118056711822521686inositol phosphate phosphatase SopBQuickGO ontologyBLASTP
11826141182754141hypothetical proteinBLASTP
118297411845361563peptidase family C69QuickGO ontologyBLASTP
118461611859801365heavy metal sensor kinase subfamilyQuickGO ontologyBLASTP
11859731186653681transcriptional activator protein IrlRQuickGO ontologyBLASTP
11867891187199411hydroxyisourate hydrolaseQuickGO ontologyBLASTP
118753211880445134-hydroxyphenylacetate 3-monooxygenase reductase componentQuickGO ontologyBLASTP
1188062118962415634-hydroxyphenylacetate 3-monooxygenase oxygenase componentQuickGO ontologyBLASTP
11898421190282441homoprotocatechuate degradation operon regulator HpaRQuickGO ontologyBLASTP
1190557119184612904-hydroxyphenylacetate degradation bifunctionalisomerasedecarboxylaseQuickGO ontologyBLASTP
1191843119330914675-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseQuickGO ontologyBLASTP