Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:265791 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2657912671431353putative magnesium transporterQuickGO ontologyBLASTP
267175267951777putative dimethyladenosine transferaseQuickGO ontologyBLASTP
2680822691311050hypothetical proteinBLASTP
2691622706161455aminoacyl-histidine dipeptidaseQuickGO ontologyBLASTP
270731271612882malonyl CoA-acyl carrier protein transacylaseQuickGO ontologyBLASTP
2717932731391347putative membrane-bound lytic murein transglycosylase DQuickGO ontologyBLASTP
273158273865708hypothetical proteinBLASTP
273885274754870putative ParB chromosome partitioning proteinQuickGO ontologyBLASTP
274762275538777putative ParA chromosome partitioning proteinQuickGO ontologyBLASTP
275754276632879hydrolaseQuickGO ontologyBLASTP
2766502776751026putative arginine deiminaseQuickGO ontologyBLASTP
277959278345387hypothetical proteinBLASTP
278348279055708hypothetical proteinBLASTP
279068279607540hypothetical proteinBLASTP
2795942808471254sigma-54-dependent transcriptional regulatorQuickGO ontologyBLASTP
2808752821431269hypothetical proteinBLASTP
2821802834841305putative Fe-S oxidoreductaseQuickGO ontologyBLASTP
283481284434954signal recognition particle-docking proteinQuickGO ontologyBLASTP
2844612855971137carboxynorspermidine decarboxylaseQuickGO ontologyBLASTP
2856072873701764aspartyl-tRNA synthetaseQuickGO ontologyBLASTP
287800288792993putative riboflavin biosynthesis proteinQuickGO ontologyBLASTP
288817289698882protoporphyrinogen oxidaseQuickGO ontologyBLASTP
289695290180486putative transcriptional regulatory proteinQuickGO ontologyBLASTP
290164290904741probable amidophosphoribosyl-transferaseQuickGO ontologyBLASTP
2910342931032070endopeptidase PepOQuickGO ontologyBLASTP