Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:2147268 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
21472682148026759hypothetical proteinBLASTP
214823021493151086transposase in ISPg1QuickGO ontologyBLASTP
214941921517072289hypothetical proteinBLASTP
21517632152509747hypothetical proteinBLASTP
21525062152943438hypothetical proteinBLASTP
21529402153641702hypothetical proteinBLASTP
215365521548361182hypothetical proteinBLASTP
215483821564181581hypothetical proteinBLASTP
215642321576671245hypothetical proteinBLASTP
21576832157919237hypothetical proteinBLASTP
215792121595041584hypothetical proteinBLASTP
21598102159983174hypothetical protein
216024421621211878glucose-inhibited division protein AQuickGO ontologyBLASTP
216215221639541803excinuclease ABC C subunitQuickGO ontologyBLASTP
21639612164413453putative D-tyrosyl-tRNA deacylaseQuickGO ontologyBLASTP
21644182164768351hypothetical proteinBLASTP
21646952165624930putative deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
21656652165826162hypothetical proteinBLASTP
21659352166909975putative polyprenyl synthetaseQuickGO ontologyBLASTP
21669672167605639hypothetical proteinBLASTP