Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:1818500 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
18185141819416903putative tRNA isopentenyltransferaseQuickGO ontologyBLASTP
181955618210701515probable 4-amino-4-deoxy-L-arabinose transferaseQuickGO ontologyBLASTP
18210981822057960putative glycosyltransferasesQuickGO ontologyBLASTP
182206818231411074conserved hypothetical protein with integral membrane domain DUF6QuickGO ontologyBLASTP
182320418251801977transcription termination factor RhoQuickGO ontologyBLASTP
18258571826375519piutative DNA-binding protein histone-like familyQuickGO ontologyBLASTP
18264081827403996hypothetical proteinBLASTP
18274441828346903formiminotransferase-cyclodeaminaseQuickGO ontologyBLASTP
182844718297181272imidazolonepropionaseQuickGO ontologyBLASTP
182981218309661155conserved hypothetical protein with nucleoside recognition domainQuickGO ontologyBLASTP
183098618321341149hypothetical proteinBLASTP
18321591832788630putative methenyltetrahydrofolate cyclohydrolaseQuickGO ontologyBLASTP
183279118342841494histidine ammonia-lyaseQuickGO ontologyBLASTP
18344851834814330hypothetical proteinBLASTP
183493718361151179serinethreonine transporterQuickGO ontologyBLASTP
183614418372501107arginineornithine transport system ATPaseQuickGO ontologyBLASTP
183732618384141089hypothetical proteinBLASTP
18384461838829384hypothetical proteinBLASTP