Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:1549744 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
15497441550247504putative anaerobic ribonucleoside-triphosphate reductase activating proteinQuickGO ontologyBLASTP
155026815526642397anaerobic ribonucleoside-triphosphate reductaseQuickGO ontologyBLASTP
155359315546781086transposase in ISPg1QuickGO ontologyBLASTP
155496515550721085S ribosomal RNAQuickGO ontologyBLASTP
15552191558051283323S ribosomal RNAQuickGO ontologyBLASTP
1558170155824677tRNA-AlaQuickGO ontology
1558248155832174tRNA-IleQuickGO ontologyBLASTP
15583311558486156hypothetical protein
15586131558771159hypothetical proteinBLASTP
15588841560358147516S ribosomal RNAQuickGO ontologyBLASTP
15606091560773165hypothetical proteinBLASTP
156116715627981632delta-1-pyrroline-5-carboxylate dehydrogenaseQuickGO ontologyBLASTP
15628751563804930putative amidinotransferaseQuickGO ontologyBLASTP
156381115650401230ornithine aminotransferaseQuickGO ontologyBLASTP
15652791565434156hypothetical proteinBLASTP
15654901566056567elongation factor PQuickGO ontologyBLASTP
15663541566569216hypothetical proteinBLASTP
15665921567098507DNA-binding protein histone-like familyQuickGO ontologyBLASTP
156724015689161677conserved hypothetical protein with predicted permease membrane regionQuickGO ontologyBLASTP