Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:1462135 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
146213514650382904excinuclease ABC A subunitQuickGO ontologyBLASTP
146510914665991491hypothetical proteinBLASTP
14665771467311735putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
146755114686361086transposase in ISPg1QuickGO ontologyBLASTP
14687661469419654hypothetical proteinBLASTP
146965714709971341hypothetical protein
14711401471316177hypothetical protein
147138014730771698TPR domain proteinQuickGO ontologyBLASTP
14732551474157903probable ABC transporter membrane proteinQuickGO ontologyBLASTP
14741571475041885probable ABC transporter membrane proteinQuickGO ontologyBLASTP
147510814763311224hypothetical protein
147633514773451011hypothetical proteinBLASTP
147734214784631122hypothetical proteinBLASTP
14784601478912453hypothetical proteinBLASTP
14791641479901738probable branched chain amino acid ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
14801421480453312hypothetical protein
14805071481484978putative para-aminobenzoate synthase component IQuickGO ontologyBLASTP
14814911482090600probable para-aminobenzoate synthase component IQuickGO ontologyBLASTP
148213514836161482hypothetical protein
148377514865852811hypothetical proteinBLASTP