Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:1344903 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
134490313474942592ClpB proteinQuickGO ontologyBLASTP
13477131348273561probable flavodoxinQuickGO ontologyBLASTP
13492721350174903hypothetical protein
13503271351196870hypothetical protein
13512141351858645hypothetical protein
135185513550463192putative ATP-binding proteinQuickGO ontologyBLASTP
13550501355760711hypothetical proteinBLASTP
13557671356297531hypothetical proteinBLASTP
135648813575731086transposase in ISPg1QuickGO ontologyBLASTP
13577851357895111hypothetical protein
135794713593561410asparaginyl-tRNA synthetaseQuickGO ontologyBLASTP
135938813607071320ribosomal large subunit pseudouridine synthase BQuickGO ontologyBLASTP
136080813621511344adenylosuccinate lyaseQuickGO ontologyBLASTP
13622861362849564probable ATPcorrinoid adenosyltransferaseQuickGO ontologyBLASTP