Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:1179008 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11787521179021270hypothetical proteinBLASTP
11790081179910903transposase in ISPg3QuickGO ontologyBLASTP
11803961181307912hypothetical protein
118133911828951557tRNA modification GTPaseQuickGO ontologyBLASTP
11832051183396192partial transposase Orf2 in ISPg5QuickGO ontologyBLASTP
11836101184512903transposase in ISPg3QuickGO ontologyBLASTP
11846661185568903transposase in ISPg3QuickGO ontologyBLASTP
11859761186878903transposase in ISPg3QuickGO ontologyBLASTP
118692411880181095hypothetical protein
118851511895251011hypothetical proteinBLASTP
118949211905201029hypothetical protein
119049511915741080hypothetical proteinBLASTP
11914921192352861hypothetical protein
11923491193278930hypothetical proteinBLASTP
119328611943621077hypothetical proteinBLASTP
119441611957861371hypothetical protein
11960791196237159hypothetical proteinBLASTP
119632311997903468putative DNA methylaseQuickGO ontologyBLASTP
119981512009001086transposase in ISPg1QuickGO ontologyBLASTP
120118112022781098GDP-mannose 46-dehydrataseQuickGO ontologyBLASTP
120227112033441074GDP-fucose synthetaseQuickGO ontologyBLASTP
120348312045021020branched-chain amino acid aminotransferaseQuickGO ontologyBLASTP
120463112063521722hypothetical proteinBLASTP
12065921206759168hypothetical proteinBLASTP
1206831120692393hypothetical proteinBLASTP
12069571207061105hypothetical protein
120731812098522535ferrous iron transport protein BQuickGO ontologyBLASTP