Pre_GI Gene

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Host: NC_010572 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010572:6293417 Streptomyces griseus subsp. griseus NBRC 13350, complete genome

Host Lineage: Streptomyces griseus; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Soil bacterium producing an antituberculosis agent. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
629341762946041188putative quinolinate synthetaseQuickGO ontologyBLASTP
62948696295225357hypothetical proteinBLASTP
629530162968841584hypothetical proteinBLASTP
62969346297131198hypothetical proteinBLASTP
62972886298262975putative carbohydrate kinaseQuickGO ontologyBLASTP
629826362996451383putative pyridoxal-phosphate-dependent aminotransferaseQuickGO ontologyBLASTP
62999196300887969putative cytochrome c oxidase subunit IIQuickGO ontologyBLASTP
630088463026201737putative cytochrome c oxidase subunit IQuickGO ontologyBLASTP
63026176303015399putative integral membrane proteinQuickGO ontologyBLASTP
630315763044101254putative secreted proteinQuickGO ontologyBLASTP
63044716304872402putative two-component system response regulatorQuickGO ontologyBLASTP
63050726305692621putative cytochrome c oxidase subunit IIIQuickGO ontologyBLASTP
63057486306557810putative cytochrome c heme-binding subunitQuickGO ontologyBLASTP
630655463076061053putative ubiquinol-cytochrome c reductase iron-sulphur subunitQuickGO ontologyBLASTP
630760363092521650putative cytochrome b subunitQuickGO ontologyBLASTP
630937663104401065putative anthranilate phosphoribosyltransferaseQuickGO ontologyBLASTP
631083263122111380putative aminotransferaseQuickGO ontologyBLASTP
63122856312566282putative AsnC-family transcriptional regulatorQuickGO ontologyBLASTP
63125636313312750putative integral membrane proteinQuickGO ontologyBLASTP
63135066313748243hypothetical proteinBLASTP
631378763151481362hypothetical proteinBLASTP
631544163164661026putative NLPP60-family secreted proteinQuickGO ontologyBLASTP