Pre_GI Gene

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Host: NC_010572 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010572:4585500 Streptomyces griseus subsp. griseus NBRC 13350, complete genome

Host Lineage: Streptomyces griseus; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Soil bacterium producing an antituberculosis agent. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
458570045870821383putative NADH dehydrogenaseQuickGO ontologyBLASTP
458752145893051785hypothetical proteinBLASTP
458935645906901335putative permease of the major facilitator superfamilyQuickGO ontologyBLASTP
45908564591413558putative MarR-family transcriptional regulatorQuickGO ontologyBLASTP
45974044598069666putative two-component system response regulatorQuickGO ontologyBLASTP
459806645993851320putative two-component system sensor kinaseQuickGO ontologyBLASTP
45994044600270867putative ABC transporter permease proteinQuickGO ontologyBLASTP
46002674601241975putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
46014134601973561putative acetyltransferaseQuickGO ontologyBLASTP
460208946037051617hypothetical proteinBLASTP
460370746051341428putative ATPGTP-binding proteinQuickGO ontologyBLASTP
460532146068711551hypothetical proteinBLASTP
460686846081271260putative integral membrane proteinQuickGO ontologyBLASTP
46081894609058870putative integral membrane proteinQuickGO ontologyBLASTP
46092404609548309putative integral membrane proteinQuickGO ontologyBLASTP
461019246126992508hypothetical proteinBLASTP
46126964613280585hypothetical proteinBLASTP