Pre_GI Gene

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Host: NC_010572 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010572:4505428 Streptomyces griseus subsp. griseus NBRC 13350, complete genome

Host Lineage: Streptomyces griseus; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Soil bacterium producing an antituberculosis agent. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
45054284506300873hypothetical proteinBLASTP
450639045076221233putative lanthionine synthetase C-like proteinQuickGO ontologyBLASTP
450761945106843066putative lantibiotic dehydrataseQuickGO ontologyBLASTP
45107714510962192putative lantibiotic precursorQuickGO ontology
451101845122531236putative O-methyltransferaseQuickGO ontologyBLASTP
45124714512890420hypothetical protein
45128874513312426putative regulatory protein containing a conserved C-terminal domainQuickGO ontologyBLASTP
451355045148031254hypothetical proteinBLASTP
45148004515327528putative acetyltransferaseQuickGO ontologyBLASTP
451544745166041158hypothetical proteinBLASTP
45167494516961213hypothetical protein
451705845180891032putative integraserecombinaseQuickGO ontologyBLASTP
45180254518822798hypothetical proteinBLASTP
451945945217052247putative DNA polymerase III gamma subunitQuickGO ontologyBLASTP
452184245230921251putative phosphoribosylglycinamide synthetaseQuickGO ontologyBLASTP
452355145252271677hypothetical protein