Pre_GI Gene

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Host: NC_010572 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010572:188500 Streptomyces griseus subsp. griseus NBRC 13350, complete genome

Host Lineage: Streptomyces griseus; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Soil bacterium producing an antituberculosis agent. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1899991914741476putative UDP-N-acetylmuramyl tripeptide synthaseQuickGO ontologyBLASTP
191655192026372hypothetical protein
1921121935001389hypothetical proteinBLASTP
194789195655867putative glutamate transporter glutamate-binding proteinQuickGO ontologyBLASTP
195740196546807hypothetical protein
196543197007465hypothetical protein
197464197859396putative acetyltransferaseQuickGO ontologyBLASTP
198260198874615hypothetical proteinBLASTP
198896199027132hypothetical proteinBLASTP
199266199601336hypothetical protein
199852200328477hypothetical protein
200565201203639hypothetical protein
201820202455636hypothetical proteinBLASTP
2032932043751083putative secreted cellulose-binding proteinQuickGO ontologyBLASTP
204852205616765putative thioesteraseQuickGO ontologyBLASTP
2059712070021032hypothetical proteinBLASTP
207370208281912putative integral membrane proteinQuickGO ontologyBLASTP
208351209253903putative LysR-family transcriptional regulatorQuickGO ontologyBLASTP
209287209964678putative two-component system response regulatorQuickGO ontologyBLASTP
2099672111511185putative two-component system sensor kinaseQuickGO ontologyBLASTP
2111482134182271putative transmembrane transport proteinQuickGO ontologyBLASTP