Pre_GI Gene

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Host: NC_010520 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010520:3788702 Clostridium botulinum A3 str. Loch Maree, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
37887023789136435ribosomal protein L13QuickGO ontologyBLASTP
37892603790000741tRNA pseudouridine synthase AQuickGO ontologyBLASTP
37900003790803804cobalt transport permease CbiQ familyQuickGO ontologyBLASTP
37908003791666867putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
37916513792499849putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
37925903792931342ribosomal protein L17QuickGO ontologyBLASTP
37929753793922948DNA-directed RNA polymerase alpha subunitQuickGO ontologyBLASTP
37939903794610621ribosomal protein S4QuickGO ontologyBLASTP
37946453795043399ribosomal protein S11QuickGO ontologyBLASTP
37950613795432372ribosomal protein S13QuickGO ontologyBLASTP
37955453795658114ribosomal protein L36QuickGO ontologyBLASTP
37956753795893219translation initiation factor IF-1QuickGO ontologyBLASTP
37959013796182282hypothetical proteinBLASTP
37961973796946750methionine aminopeptidase type IQuickGO ontologyBLASTP
37969463797596651adenylate kinaseQuickGO ontologyBLASTP
379762037988971278preprotein translocase SecY subunitQuickGO ontologyBLASTP
37988983799338441ribosomal protein L15QuickGO ontologyBLASTP
37993583799537180ribosomal protein L30QuickGO ontologyBLASTP
37995513800048498ribosomal protein S5QuickGO ontologyBLASTP
38000663800425360ribosomal protein L18QuickGO ontologyBLASTP
38004443800986543ribosomal protein L6QuickGO ontologyBLASTP
38010103801408399ribosomal protein S8QuickGO ontologyBLASTP
38014383801623186ribosomal protein S14QuickGO ontologyBLASTP
38016403802182543ribosomal protein L5QuickGO ontologyBLASTP
38022053802522318ribosomal protein L24QuickGO ontologyBLASTP
38025463802914369ribosomal protein L14QuickGO ontologyBLASTP
38029493803203255ribosomal protein S17QuickGO ontologyBLASTP
38032253803437213ribosomal protein L29QuickGO ontologyBLASTP
38034273803870444ribosomal protein L16QuickGO ontologyBLASTP
38038883804559672ribosomal protein S3QuickGO ontologyBLASTP
38045773804912336ribosomal protein L22QuickGO ontologyBLASTP
38049343805218285ribosomal protein S19QuickGO ontologyBLASTP
38052883806121834ribosomal protein L2QuickGO ontologyBLASTP
38061763806469294ribosomal protein L23QuickGO ontologyBLASTP
38064693807089621ribosomal protein L4QuickGO ontologyBLASTP
38071143807743630ribosomal protein L3QuickGO ontologyBLASTP
38078333808141309ribosomal protein S10QuickGO ontologyBLASTP
380853838097311194translation elongation factor TuQuickGO ontologyBLASTP
380977138118402070translation elongation factor GQuickGO ontologyBLASTP
38119123812382471ribosomal protein S7QuickGO ontologyBLASTP
38125433812920378ribosomal protein S12QuickGO ontologyBLASTP
38129963813238243ribosomal protein L7Ae family proteinQuickGO ontologyBLASTP
381336038168963537DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
381691738206363720DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
38209113821279369ribosomal protein L7L12QuickGO ontologyBLASTP
38213263821826501ribosomal protein L10QuickGO ontologyBLASTP
38220283822717690ribosomal protein L1QuickGO ontologyBLASTP
38227743823199426ribosomal protein L11QuickGO ontologyBLASTP
38232703823794525transcription terminationantitermination factor NusGQuickGO ontologyBLASTP
38238413824068228preprotein translocase SecE subunitQuickGO ontologyBLASTP
38241183824267150ribosomal protein L33QuickGO ontologyBLASTP
382446938256621194translation elongation factor TuQuickGO ontologyBLASTP
3825745382582076tRNA-ThrQuickGO ontologyBLASTP
3825838382591477tRNA-GlyQuickGO ontology
38259783826619642RNA polymerase sigma-H factorQuickGO ontologyBLASTP
38266933827202510hypothetical proteinBLASTP
38272053827978774RNA methyltransferase TrmH family group 3QuickGO ontologyBLASTP
38279813828733753thymidylate synthase flavin-dependentQuickGO ontologyBLASTP
38287233829163441RNase3 domain proteinQuickGO ontologyBLASTP