Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:42475 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4247542963489hydrolase NUDIX familyQuickGO ontologyBLASTP
4308143803723hypothetical proteinBLASTP
4393744725789iron-sulfur cluster-binding proteinQuickGO ontologyBLASTP
4474444905162hypothetical proteinBLASTP
4528845992705thiF domain proteinQuickGO ontologyBLASTP
46075471841110major facilitator superfamily proteinQuickGO ontologyBLASTP
4721348157945acetyltransferase GNAT familyQuickGO ontologyBLASTP
4854450045150216S ribosomal RNAQuickGO ontologyBLASTP
5026953170290223S ribosomal RNAQuickGO ontologyBLASTP
53276533921175S ribosomal RNAQuickGO ontologyBLASTP
533985347578tRNA-LysQuickGO ontologyBLASTP
5369854294597uracil-DNA glycosylase family proteinQuickGO ontologyBLASTP
5515156652150216S ribosomal RNAQuickGO ontologyBLASTP
5687659777290223S ribosomal RNAQuickGO ontologyBLASTP
59883599991175S ribosomal RNAQuickGO ontologyBLASTP
600056008278tRNA-LysQuickGO ontologyBLASTP
6042460987564RNA polymerase sigma-70 factor familyQuickGO ontologyBLASTP
60984624261443hypothetical proteinBLASTP
6307264573150216S ribosomal RNAQuickGO ontologyBLASTP
6473367634290223S ribosomal RNAQuickGO ontologyBLASTP
67685678011175S ribosomal RNAQuickGO ontologyBLASTP
678086788578tRNA-PheQuickGO ontologyBLASTP
6814468284141hypothetical proteinBLASTP
6853968712174hypothetical proteinBLASTP
6884869105258protein DltDQuickGO ontologyBLASTP
6918269295114hypothetical proteinBLASTP
7001471515150216S ribosomal RNAQuickGO ontologyBLASTP
7173974640290223S ribosomal RNAQuickGO ontologyBLASTP
74691748071175S ribosomal RNAQuickGO ontologyBLASTP
748147489178tRNA-PheQuickGO ontologyBLASTP
7503175774744peptidil-prolyl isomerase family proteinQuickGO ontologyBLASTP
7629677797150216S ribosomal RNAQuickGO ontologyBLASTP
7795780858290223S ribosomal RNAQuickGO ontologyBLASTP
80909810251175S ribosomal RNAQuickGO ontologyBLASTP
8139382136744NAD-dependent deacetylaseQuickGO ontologyBLASTP
822188229174tRNA-CysQuickGO ontologyBLASTP
8232283230909LD-carboxypeptidase family proteinQuickGO ontologyBLASTP
8326684207942transporter CorA metal ion transporter familyQuickGO ontologyBLASTP