Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:3807780 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
380778038091381359DNA repair protein radAQuickGO ontologyBLASTP
380925938116942436negative regulator of genetic competence MecBClpCQuickGO ontologyBLASTP
381169638127391044ATPguanido phosphotransferase domain proteinQuickGO ontologyBLASTP
38127443813271528UVR domain proteinQuickGO ontologyBLASTP
38132943813758465transciptional repressor CtsRQuickGO ontologyBLASTP
38141543814384231hypothetical proteinBLASTP
381473138168032073translation elongation factor GQuickGO ontologyBLASTP
3816989381706577tRNA-AsnQuickGO ontologyBLASTP
3817091381716777tRNA-AsnQuickGO ontologyBLASTP
381717538172911175S ribosomal RNAQuickGO ontologyBLASTP
38173833820284290223S ribosomal RNAQuickGO ontologyBLASTP
3820358382043477tRNA-IleQuickGO ontology
38205213822022150216S ribosomal RNAQuickGO ontologyBLASTP
3822246382232378tRNA-AlaQuickGO ontologyBLASTP
3822325382240379tRNA-MetQuickGO ontologyBLASTP
382241038225261175S ribosomal RNAQuickGO ontologyBLASTP
38226203825521290223S ribosomal RNAQuickGO ontologyBLASTP
38257453827246150216S ribosomal RNAQuickGO ontologyBLASTP
382781738291931377UDP-N-acetylmuramoylalanine--D-glutamate ligaseQuickGO ontologyBLASTP
383002838314191392glycyl-tRNA synthetaseQuickGO ontologyBLASTP
383173938332531515lysyl-tRNA synthetaseQuickGO ontologyBLASTP
38332723833754483transcription elongation factor GreAQuickGO ontologyBLASTP
38338853834712828hypothetical proteinBLASTP
38347623835733972dihydrouridine synthaseQuickGO ontologyBLASTP
38357433836519777transcriptional activator Baf familyQuickGO ontologyBLASTP
383667438383471674formate--tetrahydrofolate ligaseQuickGO ontologyBLASTP
383855038403551806ATP-dependent metalloprotease FtsHQuickGO ontologyBLASTP