Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:3759136 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
37591363759573438ribosomal protein L13QuickGO ontologyBLASTP
37596943760434741tRNA pseudouridine synthase AQuickGO ontologyBLASTP
37604343761237804cobalt transport permease CbiQ familyQuickGO ontologyBLASTP
37612343762100867putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
37620853762933849putative cobalt ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
37630243763365342ribosomal protein L17QuickGO ontologyBLASTP
37634093764356948DNA-directed RNA polymerase alpha subunitQuickGO ontologyBLASTP
37644243765044621ribosomal protein S4QuickGO ontologyBLASTP
37650793765477399ribosomal protein S11QuickGO ontologyBLASTP
37654953765866372ribosomal protein S13QuickGO ontologyBLASTP
37659793766092114ribosomal protein L36QuickGO ontologyBLASTP
37661093766327219translation initiation factor IF-1QuickGO ontologyBLASTP
37663353766616282hypothetical proteinBLASTP
37666313767380750methionine aminopeptidase type IQuickGO ontologyBLASTP
37673803768030651adenylate kinaseQuickGO ontologyBLASTP
376805437693311278preprotein translocase SecY subunitQuickGO ontologyBLASTP
37693323769772441ribosomal protein L15QuickGO ontologyBLASTP
37697923769971180ribosomal protein L30QuickGO ontologyBLASTP
37699853770482498ribosomal protein S5QuickGO ontologyBLASTP
37705003770859360ribosomal protein L18QuickGO ontologyBLASTP
37708783771420543ribosomal protein L6QuickGO ontologyBLASTP
37714443771842399ribosomal protein S8QuickGO ontologyBLASTP
37718723772057186ribosomal protein S14QuickGO ontologyBLASTP
37720743772616543ribosomal protein L5QuickGO ontologyBLASTP
37726393772956318ribosomal protein L24QuickGO ontologyBLASTP
37729803773348369ribosomal protein L14QuickGO ontologyBLASTP
37733833773637255ribosomal protein S17QuickGO ontologyBLASTP
37736593773871213ribosomal protein L29QuickGO ontologyBLASTP
37738613774304444ribosomal protein L16QuickGO ontologyBLASTP
37743223774993672ribosomal protein S3QuickGO ontologyBLASTP
37750113775346336ribosomal protein L22QuickGO ontologyBLASTP
37753683775652285ribosomal protein S19QuickGO ontologyBLASTP
37757223776555834ribosomal protein L2QuickGO ontologyBLASTP
37766103776903294ribosomal protein L23QuickGO ontologyBLASTP
37769033777523621ribosomal protein L4QuickGO ontologyBLASTP
37775483778177630ribosomal protein L3QuickGO ontologyBLASTP
37782673778575309ribosomal protein S10QuickGO ontologyBLASTP
377896537801581194translation elongation factor TuQuickGO ontologyBLASTP
378019837822672070translation elongation factor GQuickGO ontologyBLASTP
37823393782809471ribosomal protein S7QuickGO ontologyBLASTP
37829703783347378ribosomal protein S12QuickGO ontologyBLASTP
37834233783665243ribosomal protein L7Ae family proteinQuickGO ontologyBLASTP
378378737873233537DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
378734437910423699DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
37913073791678372ribosomal protein L7L12QuickGO ontologyBLASTP
37917253792225501ribosomal protein L10QuickGO ontologyBLASTP
37924273793116690ribosomal protein L1QuickGO ontologyBLASTP
37931733793598426ribosomal protein L11QuickGO ontologyBLASTP
37936693794193525transcription terminationantitermination factor NusGQuickGO ontologyBLASTP
37942403794467228preprotein translocase SecE subunitQuickGO ontologyBLASTP
37945173794666150ribosomal protein L33QuickGO ontologyBLASTP
379486837960611194translation elongation factor TuQuickGO ontologyBLASTP
3796144379621976tRNA-ThrQuickGO ontologyBLASTP
3796237379631377tRNA-GlyQuickGO ontology
37963773797018642RNA polymerase sigma-H factorQuickGO ontologyBLASTP
37970923797601510hypothetical proteinBLASTP
37976043798377774RNA methyltransferase TrmH family group 3QuickGO ontologyBLASTP
37983803799132753thymidylate synthase flavin-dependentQuickGO ontologyBLASTP
37991223799562441RNase3 domain proteinQuickGO ontologyBLASTP