Pre_GI Gene

Some Help

Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:2567911 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
25679112568138228hypothetical proteinBLASTP
25681592568407249ribosomal protein S16QuickGO ontologyBLASTP
256843825697871350signal recognition particle proteinQuickGO ontologyBLASTP
25698002570132333DNA-binding proteinQuickGO ontologyBLASTP
25703562571267912signal recognition particle-docking protein FtsYQuickGO ontologyBLASTP
257143025750113582chromosome segregation protein SMCQuickGO ontologyBLASTP
257527325763641092radical SAM domain proteinQuickGO ontologyBLASTP
25763572577061705ribonuclease IIIQuickGO ontologyBLASTP
25771862577419234acyl carrier proteinQuickGO ontologyBLASTP
257749725785041008fatty acidphospholipid synthesis protein PlsXQuickGO ontologyBLASTP
25785942578776183ribosomal protein L32QuickGO ontologyBLASTP
25787902579290501ribosomal protein L32 family proteinQuickGO ontologyBLASTP
257940825806011194acetate kinaseQuickGO ontologyBLASTP
25807412581739999phosphate acetyltransferaseQuickGO ontologyBLASTP
25820742582952879hypothetical proteinBLASTP
25833192584038720putative D-proline reductase PrdB subunit selenocysteine-containingQuickGO ontologyBLASTP
25840682584343276hypothetical proteinBLASTP
258435225864662115putative D-proline reductase PrdA proproteinQuickGO ontologyBLASTP
25864982586668171hypothetical proteinBLASTP
258669025878081119putative electron transport proteinQuickGO ontologyBLASTP