Pre_GI Gene

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Host: NC_010161 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010161:1598000 Bartonella tribocorum CIP 105476, complete genome

Host Lineage: Bartonella tribocorum; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from the blood of wild rats and from fleas obtained from wild rats. Transmission of these organisms is often through an insect vector. Once in a host, this intracellular pathogen is internalized by an actin-dependent mechanism, and primarily targets endothelial cells, although other cells can be infected. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells. This organism is genetically related to Bartonella elizabethae which was isolated from a case of endocarditis in a human.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1598076159854346850S ribosomal protein L15QuickGO ontologyBLASTP
1598564159877020750S ribosomal protein L30QuickGO ontologyBLASTP
1598802159935054930S ribosomal protein S5QuickGO ontologyBLASTP
1599463159982536350S ribosomal protein L18QuickGO ontologyBLASTP
1599838160037153450S ribosomal protein L6QuickGO ontologyBLASTP
1600411160080939930S ribosomal protein S8QuickGO ontologyBLASTP
1600824160112930630S ribosomal protein S14QuickGO ontologyBLASTP
1601154160171155850S ribosomal protein L5QuickGO ontologyBLASTP
1601704160201831550S ribosomal protein L24QuickGO ontologyBLASTP
1602031160239936950S ribosomal protein L14QuickGO ontologyBLASTP
1602543160278224030S ribosomal protein S17QuickGO ontologyBLASTP
1602794160299420150S ribosomal protein L29QuickGO ontologyBLASTP
1603007160342041450S ribosomal protein L16QuickGO ontologyBLASTP
1603457160416771130S ribosomal protein S3QuickGO ontologyBLASTP
1604167160455639050S ribosomal protein L22QuickGO ontologyBLASTP
1604559160483727930S ribosomal protein S19QuickGO ontologyBLASTP
1604853160568683450S ribosomal protein L2QuickGO ontologyBLASTP
1605708160600129450S ribosomal protein L23QuickGO ontologyBLASTP
1605998160661862150S ribosomal protein L4QuickGO ontologyBLASTP
1606621160735873850S ribosomal protein L3QuickGO ontologyBLASTP
1607386160769430930S ribosomal protein S10QuickGO ontologyBLASTP
160775616089311176elongation factor TuQuickGO ontologyBLASTP
160899716110812085elongation factor GQuickGO ontologyBLASTP
1611106161157647130S ribosomal protein S7QuickGO ontologyBLASTP
1611595161196637230S ribosomal protein S12QuickGO ontologyBLASTP
16124631613245783exodeoxyribonuclease IIIQuickGO ontologyBLASTP
16133691614274906amino-acid ABC transporter binding proteinQuickGO ontologyBLASTP
16144161615168753glutamateaspartate transport system permease protein GltJQuickGO ontologyBLASTP
16151711615887717glutamateaspartate transport system permease proteinQuickGO ontologyBLASTP
16158991616645747glutamate aspartate transport ATP-binding proteinQuickGO ontologyBLASTP
16167501617541792exopolysaccharide production negative regulator precursorQuickGO ontologyBLASTP