Pre_GI Gene

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Host: NC_009882 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009882:915500 Rickettsia rickettsii str. 'Sheila Smith', complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was isolated from from a patient with Rocky Mountain spotted fever. Causative agent for Rocky Mountain Spotted Fever. This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia rickettsii was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
915501915677177MFS type sugar transporterQuickGO ontologyBLASTP
91625691637512030S ribosomal protein S20QuickGO ontologyBLASTP
91747091754576tRNA-ValQuickGO ontologyBLASTP
91764291792027930S ribosomal protein S20QuickGO ontologyBLASTP
91793991834941150S ribosomal protein L17QuickGO ontologyBLASTP
9183609193821023DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
91940191978438430S ribosomal protein S11QuickGO ontologyBLASTP
91980992018637830S ribosomal protein S13QuickGO ontologyBLASTP
920245920883639adenylate kinaseQuickGO ontologyBLASTP
9208999222001302preprotein translocase subunit SecYQuickGO ontologyBLASTP
92220492266546250S ribosomal protein L15QuickGO ontologyBLASTP
92267992287019250S ribosomal protein L30QuickGO ontologyBLASTP
92289492342453130S ribosomal protein S5QuickGO ontologyBLASTP
92344292378934850S ribosomal protein L18QuickGO ontologyBLASTP
92380592433853450S ribosomal protein L6QuickGO ontologyBLASTP
92434792474539930S ribosomal protein S8QuickGO ontologyBLASTP
92476592507030630S ribosomal protein S14QuickGO ontologyBLASTP
92508892562754050S ribosomal protein L5QuickGO ontologyBLASTP
92562792595633050S ribosomal protein L24QuickGO ontologyBLASTP
92595792632536950S ribosomal protein L14QuickGO ontologyBLASTP
92640092663323430S ribosomal protein S17QuickGO ontologyBLASTP
92663592685021650S ribosomal protein L29QuickGO ontologyBLASTP
92684392725341150S ribosomal protein L16QuickGO ontologyBLASTP
92726892792165430S ribosomal protein S3QuickGO ontologyBLASTP
92792392828236050S ribosomal protein L22QuickGO ontologyBLASTP
92829192856927930S ribosomal protein S19QuickGO ontologyBLASTP
92859492941582250S ribosomal protein L2QuickGO ontologyBLASTP
92941692971229750S ribosomal protein L23QuickGO ontologyBLASTP
92970993033262450S ribosomal protein L4QuickGO ontologyBLASTP
93044393109064850S ribosomal protein L3QuickGO ontologyBLASTP
93109193140831830S ribosomal protein S10QuickGO ontologyBLASTP
9316499328331185elongation factor TuQuickGO ontologyBLASTP
93292193299474tRNA-GlyQuickGO ontologyBLASTP
93313093321586tRNA-TyrQuickGO ontologyBLASTP
933407934129723tRNArRNA methyltransferaseQuickGO ontologyBLASTP
934135934287153hypothetical protein
934240934692453hypothetical proteinBLASTP
9346899360801392fumarate hydrataseQuickGO ontologyBLASTP
936177936431255hypothetical proteinBLASTP
936418936741324hypothetical proteinBLASTP
9369179382751359cell division protein FtsZQuickGO ontologyBLASTP
938777939199423hypothetical proteinBLASTP
939379939735357Ecotin precursorQuickGO ontologyBLASTP
939881940453573hypothetical proteinBLASTP
9408019418651065ampG proteinQuickGO ontologyBLASTP