Pre_GI Gene

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Host: NC_009664 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009664:63230 Kineococcus radiotolerans SRS30216, complete genome

Host Lineage: Kineococcus radiotolerans; Kineococcus; Kineosporiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This organism is a coccoid bacterium originally isolated from a high-level radioactive waste cell at the Savannah River Site in Aiken, South Carolina, USA, in 2002. Radiation-resistant bacterium. Similarly to Deinococcus radiodurans, K. radiotolerans exhibits a high degree of resistance to ionizing gamma-radiation. Cells are also highly resistant to dessication. Kineococcus-like 16S rRNA gene sequences have been reported from the Mojave desert and other arid environments where these bacteria seem to be ubiquitous. Because of its high resistance to ionizing radiation and desiccation, K. radiotolerans has potential use in applications involving in situ biodegradation of problematic organic contaminants from highly radioactive environments. Moreover, comparative functional genomic characterization of this species and other known radiotolerant bacteria such as Deinococcus radiodurans and Rubrobacter xylanophilus will shed light onto the strategies these bacteria use for survival in high radiation environments, as well as the evolutionary origins of radioresistance and their highly efficient DNA repair machinery. This organism produces an orange carotenoid-like pigment. Cell growth occurs between 11-41 degresss C, pH 5-9, and in the presence of <5% NaCl and <20% glucose. Carbohydrates and alcohols are primary growth substrates.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6323064066837transcriptional regulator DeoR familyQuickGO ontologyBLASTP
64358662171860hypothetical proteinBLASTP
6661867346729short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
6739067755366putative transcriptional regulator MerR familyQuickGO ontologyBLASTP
6783268104273hypothetical protein
6830768708402PilT protein-likeQuickGO ontologyBLASTP
6886469142279hypothetical protein
6918669671486hypothetical protein
69719717672049hypothetical proteinBLASTP
71764726488856-phosphogluconate dehydrogenase NAD-bindingQuickGO ontologyBLASTP
7280873572765transcriptional regulator GntR familyQuickGO ontologyBLASTP
73709750071299extracellular solute-binding protein family 1QuickGO ontologyBLASTP
7500475960957binding-protein-dependent transport systems inner membrane componentQuickGO ontologyBLASTP
7597176852882binding-protein-dependent transport systems inner membrane componentQuickGO ontologyBLASTP
76860790942235hypothetical proteinBLASTP
7909179912822Hydroxypyruvate isomeraseQuickGO ontologyBLASTP
7990980847939D-isomer specific 2-hydroxyacid dehydrogenase NAD-bindingQuickGO ontologyBLASTP
8129082072783Methyltransferase type 11QuickGO ontologyBLASTP
8249182913423Glyoxalasebleomycin resistance proteindioxygenaseQuickGO ontologyBLASTP
8320284113912transcriptional regulator LysR familyQuickGO ontologyBLASTP
8418084962783inositol monophosphataseQuickGO ontologyBLASTP
8495985597639hypothetical proteinBLASTP