Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:4359875 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
43598754360540666DNA repair protein RadCQuickGO ontologyBLASTP
436071043619271218bifunctional phosphopantothenoylcysteine decarboxylasephosphopantothenate synthaseQuickGO ontologyBLASTP
43619054362363459deoxyuridine 5-triphosphate nucleotidohydrolaseQuickGO ontologyBLASTP
43624884363084597nucleoid occlusion proteinQuickGO ontologyBLASTP
436326043642761017putative outer membrane protein gluconolactonaseQuickGO ontologyBLASTP
43643124364953642orotate phosphoribosyltransferaseQuickGO ontologyBLASTP
43650644365780717ribonuclease PHQuickGO ontologyBLASTP
436587743670161140putative ABC-type multidrug transport system permease componentQuickGO ontologyBLASTP
43670034367920918putative ABC-type multidrug transport system ATPase componentQuickGO ontologyBLASTP
43679134368800888hypothetical proteinBLASTP
43687994368930132hypothetical proteinBLASTP
436896843706681701putative acetyltransferaseQuickGO ontologyBLASTP
43711684372031864hypothetical proteinBLASTP
43722144372960747hypothetical proteinBLASTP
437296343740211059putative methylated-DNA-protein-cysteine S-methyltransferaseQuickGO ontologyBLASTP
437407743753271251putative voltage-gated ClC-type chloride channel ClcBQuickGO ontologyBLASTP
43756034376220618hypothetical proteinBLASTP
437622643779201695NAD-dependent DNA ligase LigBQuickGO ontologyBLASTP
43781614378784624guanylate kinaseQuickGO ontologyBLASTP
43788394379114276DNA-directed RNA polymerase subunit omegaQuickGO ontologyBLASTP
437913343812532121bifunctional pppGpp synthetase II guanosine-35-bis pyrophosphate 3-pyrophosphohydrolaseQuickGO ontologyBLASTP