Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:293052 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
293052293801750KpLE2 phage-like element putative methyltransferaseQuickGO ontologyBLASTP
294073294537465hypothetical proteinBLASTP
294732295466735putative fimbriae chaparoneQuickGO ontologyBLASTP
2954322967661335putative fimbriae usherQuickGO ontologyBLASTP
2967712993262556putative fimbriae usherQuickGO ontologyBLASTP
299310300068759putative fimbriae chaparoneQuickGO ontologyBLASTP
300128300664537putative fimbriae major subunitQuickGO ontologyBLASTP
300984301142159hypothetical protein
3024703039811512diguanylate cyclasephosphodiesterase domain-containing proteinQuickGO ontologyBLASTP
305359305979621putative outer membrane proteinQuickGO ontologyBLASTP
306218306574357hypothetical proteinBLASTP
306831307304474hypothetical proteinBLASTP
307297308121825putative sensory transducerQuickGO ontologyBLASTP
308354309334981hypothetical proteinBLASTP
309928310323396hypothetical proteinBLASTP
311624312142519fimbrial subunitQuickGO ontologyBLASTP
312191312889699putative fimbrial chaparoneQuickGO ontologyBLASTP
3129693154522484putativie fimbrial usherQuickGO ontologyBLASTP
3155033166571155hypothetical protein
31713131720676tRNA-ThrQuickGO ontologyBLASTP
3173203185731254gamma-glutamyl phosphate reductaseQuickGO ontologyBLASTP
3185843196871104gamma-glutamyl kinaseQuickGO ontologyBLASTP
3200013210291029outer membrane phosphoporin protein EQuickGO ontologyBLASTP
321074321535462lipoproteinQuickGO ontologyBLASTP
324274324444171putative transcriptional regulator LysR familiyQuickGO ontologyBLASTP
324595324780186putative receptorQuickGO ontology
324994325878885membrane channel protein component of Pn transporterQuickGO ontologyBLASTP
325875326747873hypothetical proteinBLASTP