Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:2252757 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
225275722535277713-hydroxybutyrate dehydrogenaseQuickGO ontologyBLASTP
22535472254419873LysR family transcriptional regulatorQuickGO ontologyBLASTP
22546282255305678acetolactate decarboxylaseQuickGO ontologyBLASTP
225531522569941680acetolactate synthaseQuickGO ontologyBLASTP
22570182257788771acetoin reductaseQuickGO ontologyBLASTP
22581832258824642hypothetical protein
22589532259489537putative acetyl transferaseQuickGO ontologyBLASTP
225956522626813117acridine efflux pumpQuickGO ontologyBLASTP
22638332264183351putative transport proteinQuickGO ontologyBLASTP
22644722265209738response regulatorQuickGO ontologyBLASTP
226520622662671062sensor histidine protein kinase RstA regulatorQuickGO ontologyBLASTP
22670242268004981transposase IS4QuickGO ontologyBLASTP
226863622696731038L D-carboxypeptidase A in murein recyclingQuickGO ontologyBLASTP
22698522270214363TonB proteinQuickGO ontologyBLASTP
22709962271385390putative enzymeQuickGO ontologyBLASTP
22717302272206477putative acyltransferaseQuickGO ontologyBLASTP
22734102274252843subunit of heme lyaseQuickGO ontologyBLASTP
22742492274707459subunit of heme lyaseQuickGO ontologyBLASTP
22747072275261555heme lyasedisulfide oxidoreductase thioldisulfide interchange proteinQuickGO ontologyBLASTP
227525822772101953cytochrome c-type biogenesis proteinQuickGO ontologyBLASTP
22772072277665459cytochrome c biogenesisQuickGO ontologyBLASTP
22776492277879231heme exporter protein CQuickGO ontologyBLASTP
22778762278613738heme ABC transporter membrane proteinQuickGO ontologyBLASTP
22786632279322660heme ABC transporter membrane proteinQuickGO ontologyBLASTP
22793192279942624cytochrome c biogenesis protein CcmAQuickGO ontologyBLASTP
228002622813661341gluconate dehydrogenase cytochrome c subunit putativeQuickGO ontologyBLASTP
228137722831611785monooxygenase FAD-binding glucose-methanol-choline oxidoreductaseQuickGO ontologyBLASTP