Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:1956070 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
19555291956086558putative transcriptional regulatorQuickGO ontologyBLASTP
195607019571131044multidrug resistance secretion proteinQuickGO ontologyBLASTP
195711019586721563multidrug resistance protein membrane translocaseQuickGO ontologyBLASTP
195869219599661275putative beta-ketoacyl synthaseQuickGO ontologyBLASTP
19602611960671411hypothetical proteinBLASTP
19612341962214981putative transposase IS4QuickGO ontologyBLASTP
19629701963770801putative ARAC-type regulatory proteinQuickGO ontologyBLASTP
19638631964588726glutamine amidotransferaseQuickGO ontologyBLASTP
19647231965472750putative deoxygluconate dehydrogenaseQuickGO ontologyBLASTP
19657921966301510putative isochorismatase hydrolaseQuickGO ontologyBLASTP
19665621967182621phosphoglycerate mutaseQuickGO ontologyBLASTP
19678291968596768putative ARAC-type regulatory proteinQuickGO ontologyBLASTP
19687061969497792hypothetical proteinBLASTP
19695861970518933putative polysaccharide deacetylaseQuickGO ontologyBLASTP
19705311971274744putative hydantoin racemaseQuickGO ontologyBLASTP
19712741971990717transcriptional regulatorQuickGO ontologyBLASTP
197213519736311497putative allantoin permeaseQuickGO ontologyBLASTP
197373319750431311guanine deaminaseQuickGO ontologyBLASTP
19751381975797660hypothetical proteinBLASTP
197578819774881701hypothetical proteinBLASTP