Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:1914621 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
19146211915601981putative ribosexylosearabinosegalactoside ABC-type transport systems permease componentsQuickGO ontologyBLASTP
191560519166841080putative hydrolaseQuickGO ontologyBLASTP
191745419185961143putative acetylornithine deacetylaseQuickGO ontologyBLASTP
19192421919967726putative enzymeQuickGO ontologyBLASTP
19201791921084906LysR family transcriptional regulatorQuickGO ontologyBLASTP
19211261922028903LysR family transcriptional regulatorQuickGO ontologyBLASTP
192213219233401209MFS family transporterQuickGO ontologyBLASTP
19233981924018621amino acid exporter homoserine HSLQuickGO ontologyBLASTP
192422419253301107putative phosphotransferase system EIICQuickGO ontologyBLASTP
19253731925684312PTS family enzyme IIB fructose-mannitol-specificQuickGO ontologyBLASTP
19257411926211471PTS family enzyme IIA enzyme IIBCQuickGO ontologyBLASTP
19263281926975648allulose-6-phosphate 3-epimeraseQuickGO ontologyBLASTP
192702919282911263ascorbate-specific PTS system enzyme IICQuickGO ontologyBLASTP
19283221928588267PTS family protein II componentQuickGO ontologyBLASTP
19286001929037438PTS family enzyme IIA mannitol-specific crypticQuickGO ontologyBLASTP
192924619303071062putative periplasmic binding proteinLacI transcriptional regulatorQuickGO ontologyBLASTP
19304181930660243hypothetical proteinBLASTP
193085319321511299major facilitator superfamily permeaseQuickGO ontologyBLASTP
19321891932725537putative acetyltransferaseQuickGO ontologyBLASTP
19333651933943579TetRAcrR family transcriptional regulatorQuickGO ontologyBLASTP
193391919350191101putative ABC-type spermidineputrescine transport systemsQuickGO ontologyBLASTP
19352211936135915hypothetical proteinBLASTP
193617619374081233putative transporterQuickGO ontologyBLASTP
193768419392911608hypothetical proteinBLASTP
193939919404991101putative NADHflavin oxidoreductaseNADH oxidaseQuickGO ontologyBLASTP