Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:1882500 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
18828121883561750deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
188361518851201506putative pentose kinaseQuickGO ontologyBLASTP
18851821885955774DeoR transcriptional regulatorQuickGO ontologyBLASTP
18860921887006915putative ARAC-type regulatory proteinQuickGO ontologyBLASTP
18871871887456270hypothetical proteinBLASTP
188745618885531098hypothetical proteinBLASTP
18887531889124372hypothetical proteinBLASTP
18892861890266981putative helix-turn-helix AraC typeQuickGO ontologyBLASTP
189034518913551011glyceraldehyde-3-phosphate dehydrogenaseQuickGO ontologyBLASTP
1891603189168987hypothetical protein
18919921892117126hypothetical protein
18936311894275645hypothetical proteinBLASTP
18945111894813303hypothetical proteinBLASTP
18948101895346537hypothetical proteinBLASTP
189634618975271182putative dehydrogenaseQuickGO ontologyBLASTP
18975741898560987putative aldoketo reductaseQuickGO ontologyBLASTP
18988191899685867LysR family transcriptional regulatorQuickGO ontologyBLASTP
18997541899870117hypothetical protein
18998671900385519hypothetical proteinBLASTP
190051319017631251phosphoglycerate transport activatorQuickGO ontologyBLASTP
190175319037622010phosphoglycerate transporterQuickGO ontologyBLASTP
190375919049881230phosphoglycerate transporterQuickGO ontologyBLASTP
190546619067761311phosphoglycerate transporterQuickGO ontologyBLASTP