Pre_GI Gene

Some Help

Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:775357 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7753577784703114hypothetical proteinBLASTP
7785407806722133hypothetical proteinBLASTP
780840781790951hypothetical proteinBLASTP
782393782701309hypothetical proteinBLASTP
783077783832756putative carbonic anhydraseQuickGO ontologyBLASTP
785029785562534general secretion pathway protein CQuickGO ontologyBLASTP
7856437875651923general secretion pathway protein DQuickGO ontologyBLASTP
7877127890731362general secretion pathway protein EQuickGO ontologyBLASTP
7892457902611017general protein secretion proteinQuickGO ontologyBLASTP
790281790718438general secretion pathway protein GQuickGO ontologyBLASTP
790675791265591general secretion pathway protein HQuickGO ontologyBLASTP
791348791647300general secretion pathway protein IQuickGO ontologyBLASTP
792245793201957general secretion pathway protein KQuickGO ontologyBLASTP
7931857943751191general secretion pathway protein LQuickGO ontologyBLASTP
794372794833462hypothetical proteinBLASTP
794859795701843prepilin peptidaseQuickGO ontologyBLASTP
795685796050366lipoproteinQuickGO ontologyBLASTP
7968047980121209transposase for the IS285 insertion elementQuickGO ontologyBLASTP
7982477989126662-deoxyglucose-6-phosphataseQuickGO ontologyBLASTP
799323799877555yfeABCD locus regulatorQuickGO ontologyBLASTP
800006800881876hypothetical proteinBLASTP
800906801118213membrane proteinQuickGO ontologyBLASTP
801186802079894chelated iron transport system membrane proteinQuickGO ontologyBLASTP
802076802960885chelated iron transport system membrane proteinQuickGO ontologyBLASTP
802960803850891ATP-binding transport proteinQuickGO ontologyBLASTP
803847804815969periplasmic-binding proteinQuickGO ontologyBLASTP
805027805689663membrane-bound lytic murein transglycosylaseQuickGO ontologyBLASTP
805811806494684multiple drug resistance protein MarCQuickGO ontologyBLASTP
807823808035213hypothetical proteinBLASTP
8084268103541929threonyl-tRNA synthetaseQuickGO ontologyBLASTP