Pre_GI Gene

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Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:720000 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7202877218251539hypothetical proteinBLASTP
721822722016195hypothetical proteinBLASTP
7232977254922196hypothetical proteinBLASTP
725462726229768hypothetical proteinBLASTP
726834727613780hypothetical proteinBLASTP
727830728135306hypothetical proteinBLASTP
728234728554321hypothetical proteinBLASTP
728554729234681hypothetical proteinBLASTP
729658730515858hypothetical proteinBLASTP
730891731409519hypothetical proteinBLASTP
7321887331891002sugar-binding periplasmic proteinQuickGO ontologyBLASTP
7336247346281005sugar transport system permeaseQuickGO ontologyBLASTP
7347007362081509sugar transport ATP-binding proteinQuickGO ontologyBLASTP
7367477378471101sugar transport ATP-binding proteinQuickGO ontologyBLASTP
7382047394391236sugar-binding proteinQuickGO ontologyBLASTP
739599739739141ABC maltodextrin transporter permease subunitQuickGO ontologyBLASTP
7397127409081197maltodextrin transport permeaseQuickGO ontologyBLASTP
740920741771852maltodextrin permeaseQuickGO ontologyBLASTP
7417767429781203galactosidaseQuickGO ontologyBLASTP