Pre_GI Gene

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Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:3680638 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
36806383681174537hypothetical proteinBLASTP
368190236830981197hypothetical proteinBLASTP
368310936841551047M48 peptidase family proteinQuickGO ontologyBLASTP
368430136854551155hypothetical proteinBLASTP
368545236868641413hypothetical proteinBLASTP
36874813687768288hypothetical proteinBLASTP
368811236894851374hypothetical proteinBLASTP
36894573690179723hypothetical proteinBLASTP
369022936913081080modification methylaseQuickGO ontologyBLASTP
36916933691956264transposaseQuickGO ontologyBLASTP
369257836938941317hypothetical proteinBLASTP
369389136959542064hypothetical proteinBLASTP
369608836971101023transposaseQuickGO ontologyBLASTP
36971103697889780transposaseIS proteinQuickGO ontologyBLASTP
369794036990491110hypothetical proteinBLASTP
369904237010241983hypothetical proteinBLASTP
370110637023651260integraseQuickGO ontologyBLASTP
3702564370264885tRNA-LeuQuickGO ontologyBLASTP
370275337038291077hypothetical proteinBLASTP
370382937049231095hypothetical proteinBLASTP