Pre_GI Gene

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Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:2009842 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
200984220110771236membrane proteinQuickGO ontologyBLASTP
20113692011866498purine-binding chemotaxis proteinQuickGO ontologyBLASTP
201202920141942166chemotaxis protein CheAQuickGO ontologyBLASTP
201421120155121302flagellar motor protein MotBQuickGO ontologyBLASTP
20155092016396888flagellar motor protein MotAQuickGO ontologyBLASTP
20166012017182582transcriptional activator FlhCQuickGO ontologyBLASTP
20172802017537258hypothetical proteinBLASTP
201872520214242700Mg2 transport ATPase protein BQuickGO ontologyBLASTP
20218252022523699Mg2 transport ATPase protein CQuickGO ontologyBLASTP
202364920249681320hypothetical proteinBLASTP
20249222025383462methyl-accepting chemotaxis protein IIIQuickGO ontologyBLASTP
20255662025757192hypothetical proteinBLASTP
20259722026184213cold shock proteinQuickGO ontologyBLASTP
202672520299073183beta-D-galactosidaseQuickGO ontologyBLASTP
203031420313241011Zinc-binding dehydrogenaseQuickGO ontologyBLASTP
20316072032140534hypothetical proteinBLASTP