Pre_GI Gene

Some Help

Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:1682000 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
168201616836171602hypothetical proteinBLASTP
168366116870833423hypothetical proteinBLASTP
168708016883121233hypothetical proteinBLASTP
16891421689315174IS630 orfQuickGO ontologyBLASTP
16894241689744321transposaseQuickGO ontologyBLASTP
16898751690012138transposaseQuickGO ontologyBLASTP
169112016933032184hypothetical proteinBLASTP
16933191693579261hypothetical proteinBLASTP
16937331694506774hypothetical proteinBLASTP
169450316967342232hypothetical proteinBLASTP
169681916991672349hypothetical proteinBLASTP
169917017018122643ATPase subunit of ATP-dependent proteaseQuickGO ontologyBLASTP
17022001702691492hypothetical proteinBLASTP
17022331702718486hypothetical proteinBLASTP
170269517044311737hypothetical proteinBLASTP
17044311705117687membrane proteinQuickGO ontologyBLASTP
170511417064661353hypothetical proteinBLASTP
170647817080221545hypothetical proteinBLASTP
17080711708571501hypothetical proteinBLASTP
17095601710408849acyl transferaseQuickGO ontologyBLASTP
17107931711281489hypothetical proteinBLASTP
17113201712108789short chain dehydrogenaseQuickGO ontologyBLASTP
17121111712887777polyketide biosynthesis enoyl-CoA hydrataseQuickGO ontologyBLASTP
17128651713584720enoyl-CoA hydrataseQuickGO ontologyBLASTP
171357717148151239putative hydroxymethylglutaryl-coenzyme A synthaseQuickGO ontologyBLASTP
17148311715577747beta-ketoacyl-acyl-carrier-protein reductaseQuickGO ontologyBLASTP
171557017168531284beta-ketoacyl-acyl-carrier-protein synthaseQuickGO ontologyBLASTP
171684317173675253R-hydroxymyristoyl-ACP dehydrataseQuickGO ontologyBLASTP