Pre_GI Gene

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Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:1414985 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
14149851415200216membrane proteinQuickGO ontologyBLASTP
14151971415502306hypothetical proteinBLASTP
14161771416596420hypothetical proteinBLASTP
14166681417627960transposaseQuickGO ontologyBLASTP
14178471418191345hypothetical proteinBLASTP
14187731418946174hypothetical proteinBLASTP
14200021420559558hypothetical proteinBLASTP
1420857142094286tRNA-LeuQuickGO ontologyBLASTP
1420953142102674tRNA-CysQuickGO ontologyBLASTP
1421079142115476tRNA-GlyQuickGO ontology
14212991421847549phosphatidylglycerophosphate synthetaseQuickGO ontologyBLASTP
142190614237591854excinuclease ABC subunit CQuickGO ontologyBLASTP
14237311424387657response regulatorQuickGO ontologyBLASTP
14250501425274225hypothetical proteinBLASTP
14253991425743345membrane proteinQuickGO ontologyBLASTP
14257711426025255hypothetical proteinBLASTP
14263651426916552attachment invasion locus proteinQuickGO ontologyBLASTP
1427603142767876tRNA-LysQuickGO ontologyBLASTP
142803114294551425D-alanineD-serineglycine permeaseQuickGO ontologyBLASTP
142958114307591179N-acetylneuraminic acid mutarotaseQuickGO ontologyBLASTP
14311531431752600TrpR binding protein WrbAQuickGO ontologyBLASTP
143183814331421305hypothetical proteinBLASTP
143315314342831131hypothetical proteinBLASTP