Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:877904 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
878740879213474putative ATP binding proteinQuickGO ontologyBLASTP
879225879734510putative integral membrane proteinQuickGO ontologyBLASTP
879787880134348putative plamid toxin PemK proteinQuickGO ontologyBLASTP
880136880372237putative transcription regulatorQuickGO ontologyBLASTP
880731881381651hypothetical proteinBLASTP
881660882028369Death-on-curing protein prophage related proteinQuickGO ontologyBLASTP
882025882183159hypothetical proteinBLASTP
8825728835791008Putative transposase for IS1106A3QuickGO ontologyBLASTP
8847298859911263putative HlyD family secretion proteinQuickGO ontologyBLASTP
8859938880892097putative ABC transporterQuickGO ontologyBLASTP
888125888460336putative integral membrane proteinQuickGO ontologyBLASTP
888453888872420putative integral membrane proteinQuickGO ontologyBLASTP
8888768900241149hypothetical proteinBLASTP
890118890234117hypothetical protein
890200890403204putative ParB proteinQuickGO ontologyBLASTP
891437892411975Putative transposase for IS1106A3 fragmentQuickGO ontologyBLASTP
8937988960232226putative isocitrate dehydrogenaseQuickGO ontologyBLASTP
8964568975711116CMP-N-acetylneuraminate-beta-galactosamide- alpha-23-sialyltransferaseQuickGO ontologyBLASTP
897736898194459putative C-type cytochromeQuickGO ontologyBLASTP
898313899134822putative oxidoreductaseQuickGO ontologyBLASTP
899185899631447putative acyl-CoA hydrolaseQuickGO ontologyBLASTP