Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:549351 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5493515510121662putative electron transfer flavoprotein-ubiquinone oxidoreductaseQuickGO ontologyBLASTP
551142551684543putative peptidaseQuickGO ontologyBLASTP
552629553282654putative transposaseQuickGO ontologyBLASTP
553888554703816putative outer membrane proteinQuickGO ontologyBLASTP
5547205608096090iron-regulated protein FrpCQuickGO ontologyBLASTP
561089562003915putative periplasmic binding proteinQuickGO ontologyBLASTP
562080562955876putative ABC-transporter membrane proteinQuickGO ontologyBLASTP
562979563734756putative ABC-transporter ATP-binding proteinQuickGO ontologyBLASTP
564026564391366putative 50S ribosomal protein L19QuickGO ontologyBLASTP
564407565156750putative tRNA guanine-N1-methyltransferaseQuickGO ontologyBLASTP
565156565665510putative 16S rRNA processing proteinQuickGO ontologyBLASTP
565681565926246putative 30S ribosomal protein S16QuickGO ontologyBLASTP
5659715683972427hypothetical proteinBLASTP