Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:1829500 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
182965718312311575putative phosphate permeaseQuickGO ontologyBLASTP
183155318326561104hypothetical proteinBLASTP
18327751833716942adhesin MafA2QuickGO ontologyBLASTP
183372018354831764adhesin MafB2QuickGO ontologyBLASTP
18354861835809324hypothetical proteinBLASTP
18358621836095234hypothetical proteinBLASTP
18362221836764543hypothetical proteinBLASTP
18375821837980399hypothetical proteinBLASTP
18380111838388378hypothetical proteinBLASTP
18385201838984465hypothetical proteinBLASTP
18389931839265273hypothetical proteinBLASTP
18394321839662231hypothetical proteinBLASTP
18398131840442630hypothetical proteinBLASTP
18403931840878486hypothetical proteinBLASTP
18410991841458360putative lipoproteinQuickGO ontologyBLASTP
18414701841805336hypothetical proteinBLASTP
184210918432331125hypothetical proteinBLASTP
18433201843595276hypothetical proteinBLASTP
18436121844379768putative outer membrane hypothetical proteinQuickGO ontologyBLASTP
18448041845079276hypothetical proteinBLASTP
184507618463591284putative integral membrane signal transducer proteinQuickGO ontologyBLASTP
184651318479311419glutamine synthetaseQuickGO ontologyBLASTP
18487531849562810shikimate dehydrogenaseQuickGO ontologyBLASTP
18495641850265702monofunctional biosynthetic peptidoglycan transglycosylaseQuickGO ontologyBLASTP
1850468185054376tRNA-PheQuickGO ontologyBLASTP
18507341851498765putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
18515421852072531putative outer membrane hypothetical proteinQuickGO ontologyBLASTP
18520531852634582putative periplasmic hypothetical proteinQuickGO ontologyBLASTP
18526311853167537hypothetical proteinBLASTP