Pre_GI Gene

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Host: NC_008600 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008600:5046000 Bacillus thuringiensis str. Al Hakam, complete genome

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
504603750470441008ABC transporter ATP-binding protein and transcriptional regulator LytTr DNA-binding domain fusion proteinQuickGO ontologyBLASTP
504717250481911020stage II sporulation protein DQuickGO ontologyBLASTP
504855250498561305UDP-N-acetylglucosamine 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
50498965050606711hypothetical proteinBLASTP
505110250526221521NADH dehydrogenase I subunit NQuickGO ontologyBLASTP
505262450541261503NADH dehydrogenase I subunit MQuickGO ontologyBLASTP
505412350559851863NADH dehydrogenase I subunit LQuickGO ontologyBLASTP
50563225056846525NADH dehydrogenase I subunit JQuickGO ontologyBLASTP
505728850582891002NADH dehydrogenase I subunit HQuickGO ontologyBLASTP
505828950593891101NADH dehydrogenase I subunit DQuickGO ontologyBLASTP
505939450605571164NADH dehydrogenase I subunit CQuickGO ontologyBLASTP
50605545061093540NADH dehydrogenase I subunit BQuickGO ontologyBLASTP
506172250644512730sensory boxGGDEF family proteinQuickGO ontologyBLASTP
50645265065197672hypothetical proteinBLASTP
50652275066018792hypothetical proteinBLASTP
50661525066553402ATP synthase F1 epsilon subunitQuickGO ontologyBLASTP
506657450679831410ATP synthase F1 beta subunitQuickGO ontologyBLASTP
50681035068963861ATP synthase F1 gamma subunitQuickGO ontologyBLASTP
506937650708931518ATP synthase F1 alpha subunitQuickGO ontologyBLASTP
50708965071438543ATP synthase F1 delta subunitQuickGO ontologyBLASTP
50714355071941507ATP synthase F0 subunit BQuickGO ontologyBLASTP
50720715072289219ATP synthase F0 subunit CQuickGO ontologyBLASTP
50723465073065720ATP synthase F0 subunit AQuickGO ontologyBLASTP
50742015074830630uracil phosphoribosyltransferaseQuickGO ontologyBLASTP
507510350763471245serine hydroxymethyltransferaseQuickGO ontologyBLASTP
50765615077166606hypothetical proteinBLASTP
50772005077643444ribose 5-phosphate isomerase BQuickGO ontologyBLASTP
50777405078180441protein tyrosine phosphataseQuickGO ontologyBLASTP
50784275078924498PTS system glucose-specific IIA componentQuickGO ontologyBLASTP
50793125079698387possible membrane proteinQuickGO ontologyBLASTP
50798585080469612possible flavin reductaseQuickGO ontologyBLASTP
50811305081678549possible integral membrane proteinQuickGO ontologyBLASTP
508175650827961041sua5yciOyrdCywlC family proteinQuickGO ontologyBLASTP
50829055083363459hypothetical proteinBLASTP
50834135084288876stage II sporulation protein RQuickGO ontologyBLASTP
50843925085243852modification methylase HemK familyQuickGO ontologyBLASTP
508524350863191077peptide chain release factor 1QuickGO ontologyBLASTP
50864545087041588thymidine kinaseQuickGO ontologyBLASTP
508779950890701272transcription termination factor RhoQuickGO ontologyBLASTP
50893465090311966fructose-16-bisphosphatase class IIQuickGO ontologyBLASTP
509042950917181290UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2QuickGO ontologyBLASTP
50920495092906858fructose-bisphosphate aldolase class IIQuickGO ontologyBLASTP
50931175093494378stage 0 sporulation protein FQuickGO ontologyBLASTP
50936875094211525hypothetical proteinBLASTP
509424350958501608CTP synthaseQuickGO ontologyBLASTP
50961085096638531DNA-directed RNA polymerase delta subunitQuickGO ontologyBLASTP
50967945097432639transcriptional regulator TetR familyQuickGO ontologyBLASTP
509748850986271140short-chain acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
509864950997941146short-chain acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
509985251007038523-hydroxyacyl-CoA dehydrogenaseQuickGO ontologyBLASTP