Pre_GI Gene

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Host: NC_008600 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008600:4898000 Bacillus thuringiensis str. Al Hakam, complete genome

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
489803248990901059possible periplasmic component of efflux systemQuickGO ontologyBLASTP
489905649012662211ABC-type bacteriocin transporter family proteinQuickGO ontologyBLASTP
49013774901562186hypothetical proteinBLASTP
49015914901785195hypothetical proteinBLASTP
49018334902027195hypothetical proteinBLASTP
49027404902925186hypothetical proteinBLASTP
490381749067022886excinuclease ABC subunit AQuickGO ontologyBLASTP
490669949086751977excinuclease ABC subunit BQuickGO ontologyBLASTP
49093044909924621hypothetical proteinBLASTP
49099214910685765transcriptional regulator MerR familyQuickGO ontologyBLASTP
49111564911536381hypothetical proteinBLASTP
491218149132391059hypothetical proteinBLASTP
49133274914247921transcriptional regulator LysR familyQuickGO ontologyBLASTP
49142994914667369transcriptional regulator MerR familyQuickGO ontologyBLASTP
49146724915217546FMN reductase NADPH-dependentQuickGO ontologyBLASTP
49152204915579360ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
49156854916026342hypothetical proteinBLASTP
491606449177791716multidrug resistance ABC transporter ATP-binding and permease componentQuickGO ontologyBLASTP
491809349192951203hypothetical proteinBLASTP
491938749208741488carboxyl-terminal proteaseQuickGO ontologyBLASTP
49209424921883942cell division ABC transporter permease componentQuickGO ontologyBLASTP
49218254922511687cell division ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
49227984923121324cytochrome c-551QuickGO ontologyBLASTP
49235584924538981peptide chain release factorQuickGO ontologyBLASTP
492480149273082508preprotein translocase SecA subunitQuickGO ontologyBLASTP
49275854928127543ribosomal subunit interface proteinQuickGO ontologyBLASTP
49284514928654204cold shock proteinQuickGO ontologyBLASTP
49287754929479705comF operon protein 3QuickGO ontologyBLASTP
492947949308281350comF operon protein 1QuickGO ontologyBLASTP
493095649322661311endopeptidase lytE NLPP60 family fusion proteinQuickGO ontologyBLASTP
49330084933850843degV family proteinQuickGO ontologyBLASTP