Pre_GI Gene

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Host: NC_008600 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008600:3643905 Bacillus thuringiensis str. Al Hakam, complete genome

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
364390536452031299zinc proteaseQuickGO ontologyBLASTP
36452333646132900polysaccharide deacetylaseQuickGO ontologyBLASTP
364628436484222139polyribonucleotide nucleotidyltransferaseQuickGO ontologyBLASTP
36485833648852270ribosomal protein S15 30S ribosomal protein S15QuickGO ontologyBLASTP
364895336499601008riboflavin biosynthesis protein CQuickGO ontologyBLASTP
36499683650891924tRNA pseudouridine synthase BQuickGO ontologyBLASTP
36509783651334357ribosome-binding factor AQuickGO ontologyBLASTP
36513503651631282hypothetical proteinBLASTP
365162836537482121translation initiation factor IF-2QuickGO ontologyBLASTP
36536933654004312ribosomal protein L7Ae family 50S ribosomal proteinQuickGO ontologyBLASTP
36540053654286282hypothetical proteinBLASTP
365428936553951107N utilization substance protein AQuickGO ontologyBLASTP
36554133655937525hypothetical proteinBLASTP
365621636576671452DNA polymerase III alpha subunitQuickGO ontologyBLASTP
365772936595551827possible group II intronQuickGO ontologyBLASTP
366027136631892919DNA polymerase III alpha subunitQuickGO ontologyBLASTP