Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:5234467 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
523446752357351269dioxygenase large subunitQuickGO ontologyBLASTP
52357325236520789enoyl-CoA hydrataseQuickGO ontologyBLASTP
52365175237320804probable enoyl-CoA hydrataseQuickGO ontologyBLASTP
52373175238087771enoyl-CoA hydrataseisomerase family proteinQuickGO ontologyBLASTP
523808452388337503-oxoacyl-acyl-carrier-protein reductaseQuickGO ontologyBLASTP
52389485239745798oxidoreductase short chain dehydrogenasereductase family proteinQuickGO ontologyBLASTP
523988152415901710putative dehydrogenaseQuickGO ontologyBLASTP
52419675242413447TetR family protein transcriptional regulator putativeQuickGO ontologyBLASTP
52427105242985276transposaseQuickGO ontologyBLASTP
52429855243902918transposaseQuickGO ontologyBLASTP
52443885244513126hypothetical proteinBLASTP
524457952459641386fatty aldehyde dehydrogenaseQuickGO ontologyBLASTP
524598352467747923-alpha-hydroxysteroid dehydrogenaseQuickGO ontologyBLASTP
524678252480471266NikQ proteinQuickGO ontologyBLASTP
524804452495071464acyl-CoA synthaseQuickGO ontologyBLASTP
52495865249990405hypothetical proteinBLASTP
525016652512421077ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
52514865252076591putative transcriptional regulatorQuickGO ontologyBLASTP
525213852531421005p40 proteinQuickGO ontologyBLASTP