Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:1911491 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
191149119126211131amidohydrolase 2QuickGO ontologyBLASTP
191262619138251200thiolaseQuickGO ontologyBLASTP
19138221914271450acyl dehydrataseQuickGO ontologyBLASTP
19142781914487210hypothetical protein
19145071915322816carveol dehydrogenase -trans-carveol dehydrogenaseQuickGO ontologyBLASTP
191557219168071236aldehyde dehydrogenaseQuickGO ontologyBLASTP
19169871917277291hypothetical protein
19173201917577258hypothetical protein
19175701917965396hypothetical proteinBLASTP
191794219192461305transposase Mutator family proteinQuickGO ontologyBLASTP
19193991920034636hypothetical proteinBLASTP
19200431920873831NAD binding domain of 6-phosphogluconate dehydrogenase family proteinQuickGO ontologyBLASTP
192088419219691086putative phosphotransferaseQuickGO ontologyBLASTP
192201419230751062hypothetical proteinBLASTP
19231281923763636transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
192389419253091416amidohydrolase family proteinQuickGO ontologyBLASTP
19261551926667513cytochrome c oxidase subunit III family proteinQuickGO ontologyBLASTP
19267241926945222hypothetical protein
19269491927530582hypothetical proteinBLASTP
19275341928457924short chain dehydrogenaseQuickGO ontologyBLASTP
19284541928675222hypothetical proteinBLASTP
19288851929670786enoyl-CoA hydrataseisomeraseQuickGO ontologyBLASTP
192968219309561275NikQ proteinQuickGO ontologyBLASTP
193111119321931083oxidoreductase family protein NAD-binding Rossmann fold proteinQuickGO ontologyBLASTP
19321901932696507hypothetical protein
193285919339921134alcohol dehydrogenase BQuickGO ontologyBLASTP