Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:1792318 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
17923181793238921hypothetical proteinBLASTP
17932631794111849oxidoreductase short chain dehydrogenasereductase family proteinQuickGO ontologyBLASTP
17941131795030918alphabeta hydrolase fold domain proteinQuickGO ontologyBLASTP
17951631795279117hypothetical protein
17952811795697417hypothetical proteinBLASTP
17958571796525669TetR-family protein transcriptional regulatorQuickGO ontologyBLASTP
17966361797781114623-dihydroxybiphenyl-12-dioxygenaseQuickGO ontologyBLASTP
179777817987199422-hydroxyhepta-24-diene-17-dioate isomeraseQuickGO ontologyBLASTP
179882518002521428monooxygenase FAD-bindingQuickGO ontologyBLASTP
180029118015651275transposase Mutator family proteinQuickGO ontologyBLASTP
18017031802380678LprM proteinQuickGO ontologyBLASTP
180242118038481428virulence factor mce family proteinQuickGO ontologyBLASTP
18051131805910798short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
18059241806793870carveol dehydrogenaseQuickGO ontologyBLASTP
18069241807751828enoyl-CoA hydrataseisomerase family proteinQuickGO ontologyBLASTP
180781618085957803-hydroxyacyl-CoA dehydrogenase type-2QuickGO ontologyBLASTP
180860518097021098putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
180969918108471149putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP