Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:1349579 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
134957913514591881drug transporterQuickGO ontologyBLASTP
135146413548773414ATPaseQuickGO ontologyBLASTP
135492913561131185NikQ proteinQuickGO ontologyBLASTP
13561461356700555hypothetical proteinBLASTP
13567341357504771short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
135755313581646124-carboxymuconolactone decarboxylase domain proteinQuickGO ontologyBLASTP
13582021359038837carveol dehydrogenaseQuickGO ontologyBLASTP
13593131359798486hypothetical proteinBLASTP
135991213606467352-hydroxycyclohexanecarboxyl-CoA dehydrogenaseQuickGO ontologyBLASTP
13606971360918222hypothetical protein
136091513622791365cytochrome P450 superfamily proteinQuickGO ontologyBLASTP
136343313644761044homoserine dehydrogenase NAD binding domain family proteinQuickGO ontologyBLASTP
13645501365137588LprE proteinQuickGO ontology
136525813669581701ATP-dependent rna helicase deaddeah box family proteinQuickGO ontologyBLASTP
136695513680941140putative acyltransferase putativeQuickGO ontologyBLASTP
13682831368876594transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
136887613701051230putative cytochrome P450 130QuickGO ontologyBLASTP
137024513716121368oxidoreductase FAD-bindingQuickGO ontologyBLASTP
137163313728501218transporter major facilitator family proteinQuickGO ontologyBLASTP