Pre_GI Gene

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Host: NC_008595 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008595:1176658 Mycobacterium avium 104, complete genome

Host Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: It was derived from an AIDS patient and has been characterized for virulence in the murine model of low-dose aerosol infection in that it could colonize the lung, proliferate within the tissue and disseminate to other organs. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
11766581177254597hypothetical protein
117745211783428914-hydroxy-3-methylbut-2-enyl diphosphate reductaseQuickGO ontologyBLASTP
117835911794651107hypothetical protein
117970411807561053GTP-binding protein YchFQuickGO ontologyBLASTP
11809471181222276transposaseQuickGO ontologyBLASTP
118224211835161275transposase Mutator family proteinQuickGO ontologyBLASTP
11838231184032210HNH endonuclease putativeQuickGO ontologyBLASTP
118429511855991305transposase Mutator family proteinQuickGO ontologyBLASTP
118570811869701263transposase Mutator family proteinQuickGO ontologyBLASTP
11871071187313207hypothetical proteinBLASTP
11873001187671372PIN domain putativeQuickGO ontologyBLASTP
11878041188211408hypothetical proteinBLASTP
11882771189014738short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
11891101189715606transcriptional regulatorQuickGO ontologyBLASTP
11898171190215399glyoxalase family proteinQuickGO ontologyBLASTP
11902841190667384secreted protein antigenQuickGO ontology
11907371191069333hypothetical protein
11913641191774411hypothetical protein
11921851192508324antibiotic biosynthesis monooxygenaseQuickGO ontologyBLASTP
11925131193196684hypothetical proteinBLASTP
11933231193511189hypothetical protein
11934691194287819adenylate and Guanylate cyclase catalytic domain proteinQuickGO ontologyBLASTP
119441911958281410glucose-6-phosphate 1-dehydrogenaseQuickGO ontologyBLASTP
1195845119686710236-phosphogluconate dehydrogenase decarboxylatingQuickGO ontologyBLASTP