Pre_GI Gene

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Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:692944 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
692944693099156hypothetical protein
693071693781711hypothetical proteinBLASTP
693873693974102hypothetical protein
6940786955381461rrf2 family protein cysteine desulfuraseQuickGO ontologyBLASTP
6955676968051239cysteine desulfuraseQuickGO ontologyBLASTP
696821697213393FeS cluster assembly scaffold IscUQuickGO ontologyBLASTP
697239697604366iron-sulfur cluster assembly accessory proteinQuickGO ontologyBLASTP
697597698037441co-chaperone protein hscBQuickGO ontologyBLASTP
6980286998061779chaperone protein HscAQuickGO ontologyBLASTP
699861700211351iron-sulfur cluster-binding proteinQuickGO ontologyBLASTP
7002417014101170hypothetical protein
70201770210993hypothetical protein
702075702224150hypothetical protein
7029317055702640hypothetical proteinBLASTP
705884706087204hypothetical protein
70625870635396hypothetical protein
706501706602102hypothetical protein
706914707321408cytochrome c biogenesis family proteinQuickGO ontologyBLASTP
709047709883837phage conserved hypothetical protein BR0599QuickGO ontologyBLASTP
71110271120099hypothetical protein
711865712752888S-adenosyl-methyltransferase MraWQuickGO ontologyBLASTP