Pre_GI Gene

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Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:441782 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4417824430681287seryl-tRNA synthetaseQuickGO ontologyBLASTP
4432544444891236putative DNA recombination protein RmuCQuickGO ontologyBLASTP
444659444817159hypothetical protein
445011445634624hypothetical protein
445920446858939tRNA delta2-isopentenylpyrophosphate transferaseQuickGO ontologyBLASTP
447263447730468hypothetical proteinBLASTP
447896448882987hypothetical proteinBLASTP
4489524502321281NADH dehydrogenase I F subunitQuickGO ontologyBLASTP
451464452069606NADH dehydrogenase I J subunitQuickGO ontologyBLASTP
452113452439327NADH dehydrogenase I K subunitQuickGO ontologyBLASTP
4525594544361878NADH dehydrogenase I L subunitQuickGO ontologyBLASTP
4544334559081476NADH dehydrogenase I M subunitQuickGO ontologyBLASTP
4559104573041395NADH dehydrogenase I N subunitQuickGO ontologyBLASTP
45740145855811581-deoxy-D-xylulose 5-phosphate reductoisomeraseQuickGO ontologyBLASTP
4587194605121794hypothetical proteinBLASTP