Pre_GI Gene

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Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:411630 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
411630412424795ABC 3 transport family proteinQuickGO ontologyBLASTP
412643413407765hypothetical protein
413710414279570ubiquinol-cytochrome c reductase iron-sulfur subunitQuickGO ontologyBLASTP
4142884155141227ubiquinol-cytochrome c reductase cytochrome bQuickGO ontologyBLASTP
415516416268753ubiquinol-cytochrome c reductase cytochrome c1QuickGO ontologyBLASTP
4170214187451725hypothetical proteinBLASTP
4188114204211611hypothetical proteinBLASTP
4221374238161680hypothetical proteinBLASTP
424160424357198hypothetical protein
4253944268001407glutamyl-tRNA synthetaseQuickGO ontologyBLASTP
426766426903138hypothetical protein
42692342699674tRNA-ThrQuickGO ontology
427134427940807formamidopyrimidine-DNA glycosylaseQuickGO ontologyBLASTP
429245429418174hypothetical protein
429456429617162hypothetical protein
4300724316011530propionyl-CoA carboxylase beta subunitQuickGO ontologyBLASTP