Pre_GI Gene

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Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:1451804 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
12226832562DNA polymerase IQuickGO ontologyBLASTP
28383548711ribulose-phosphate 3-epimeraseQuickGO ontologyBLASTP
36244358735putative ABC transporter permease proteinQuickGO ontologyBLASTP
43655090726ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
61517008858hypothetical proteinBLASTP
145343314545721140P44-11 outer membrane proteinQuickGO ontologyBLASTP
14546231454745123hypothetical protein
14549431455551609hypothetical protein
14556281456533906cation efflux family proteinQuickGO ontologyBLASTP
1456540145661273tRNA-ValQuickGO ontology
14566471457291645putative heme exporter protein CcmBQuickGO ontologyBLASTP
14574171457851435putative dnaK suppressor proteinQuickGO ontologyBLASTP
146019814624202223type IV secretion system protein VirD4QuickGO ontologyBLASTP
14624721463470999type IV secretion system protein VirB11QuickGO ontologyBLASTP
146351714648211305type IV secretion system protein VirB10QuickGO ontologyBLASTP
14648451465690846type IV secretion system protein VirB9QuickGO ontologyBLASTP
14656741466390717type IV secretion protein VirB8QuickGO ontologyBLASTP
1466475146657399hypothetical protein
146830814694231116putative DNA replication and repair protein RecFQuickGO ontologyBLASTP
14695581469677120hypothetical protein
14702731470410138hypothetical protein
14707711471214444hypothetical protein