Pre_GI Gene

Some Help

Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:107950 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
107950108243294uridylate kinase truncationQuickGO ontologyBLASTP
10893210903099hypothetical protein
109222109833612riboflavin synthase alpha subunitQuickGO ontologyBLASTP
1103981138173420transcription-repair coupling factorQuickGO ontologyBLASTP
113823113993171hypothetical protein
114020114472453ribonuclease H1QuickGO ontologyBLASTP
1145111175103000acetamidaseformamidase family proteinQuickGO ontologyBLASTP
117715118449735uridylate kinaseQuickGO ontologyBLASTP
118458119012555ribosome recycling factorQuickGO ontologyBLASTP
119550120257708putative phosphatidate cytidylyltransferaseQuickGO ontologyBLASTP
120721120930210hypothetical protein
122729122941213hypothetical protein
1233861268743489hypothetical protein
127175127306132hypothetical protein
127341128075735phosphoribosylaminoimidazole-succinocarboxamide synthaseQuickGO ontologyBLASTP
1281901294521263histidyl-tRNA synthetaseQuickGO ontologyBLASTP
129534129689156hypothetical protein
129926130672747thioldisulfide oxidoreductaseQuickGO ontologyBLASTP